Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc
Journal website

Case Report

Volume 3, Number 3, September 2014, pages 108-113

A Rare Case of Histologic Benign Struma Ovarii With Distant Metastasis


Figure 1.
Figure 1. Abdominal ultrasonography (A) and abdominal CT with contrast enhancement (B, C) revealed multiple mixed cystic lesions over bilateral ovaries and multiple hyper-vascular tumors widespread to peritoneum, liver and lung (indicated by arrowhead). (D) Disseminated tumor seeding to peritoneum and colon (peritoneal strumosis) was demonstrated during the operation.
Figure 2.
Figure 2. Histology of ovary and excised tumor from peritoneum and liver: (A) H&E stain (× 400) in ovarian tissue; (B) peritoneal tumor seeding; (C) liver seeding; and (D) thyroglobulin stain of liver seeding.
Figure 3.
Figure 3. Imaging studies of SPECT (A), PET-FDG (B) and I131 (3 mCi) pre-treatment scan of 6 h (C) and 24 h (D). There were multiple sites of intense radiotracer uptake accumulation over the right lower lung, liver and pelvis. Relatively less intense uptake was seen over the left lower lung, right peritoneal cavity and uterine adnexa.
Figure 4.
Figure 4. Immunohistochemistry (× 200) of the expressions of VEGF (left panel) and p53 (right panel) for normal thyroid (A, B), excised ovary(C, D), peritoneal (E, F) and liver seedings (G, H).