J Clin Gynecol Obstet

Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc

Journal website http://www.jcgo.org

Original Article

Volume 5, Number 3, September 2016, pages 85-91

Mutations in the Gene for Factor V Leiden and G20210A Prothrombin Polymorphism in Women With Recurrent Spontaneous Abortion: A Retrospective Study in a Brazilian Population

Figures

Figure 1. Agarose gel of FVL. Slot 1: molecular marker 100 pb. Slot 2: negative control. Slots 3, 4, 5 and 7: genotype homozygous wild. Slot 6: genotype heterozygous.

Figure 2. Agarose gel polymorphism in the prothrombin gene. Slot 1: molecular marker 100 pb. Slot 2: negative control. Slots 3, 4, 5, 6 and 8: genotype homozygous wild. Slot 7: genotype heterozygous.

Tables

**Table 1.** Cytogenetic Results and Frequencies of Chromosomal Abnormalities
Chromosomal abnormalities	No. (%)	Trisomy	Triploidy	Tetraploidy	Double trisomy	Monosomy	Structural abnormalities
Aneuploidy	97 (78.87)	91 (74%)			4 (3.25%)	2 (1.65%)
Euploidy	22 (17.88)		18 (14.60%)	4 (3.25%)
Structural abnormalities	4 (3.25)						4 (3.25%)
Total	123	91	18	4	4	2	4

**Table 2.** Frequency of Polymorphisms in Abnormal and Normal Abortions
Polymorphism	Genotype	Abnormal		Normal
Polymorphism	Genotype	No.	%	No.	%
FVL (G1691A)	Homozygous wild	117	97.5	107	92.3
	Homozygous	3	2.5	9	7.7
	Total	120	100.0	116	100.0
Prothrombin (G20210A)	Homozygous wild	113	99.1	108	95.6
	Homozygous	1	0.9	5	4.4
	Total	114	100.0	113	100.0