Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc
Journal website http://www.jcgo.org

Case Report

Volume 6, Number 1, March 2017, pages 23-27


Primary Neuroendocrine Carcinoma of the Uterine Cervix Treated With Complete Surgical Resection and Adjuvant Combination Chemotherapy

Figures

Figure 1.
Figure 1. Pelvic MRI images of T2 intensified (1-1: sagittal section; 1-2: transverse section). Uterine cervical tumor of 3 cm in diameter was visualized on MRI (arrow). The tumor invaded to the right parametrial space with interruption of the stromal ring (arrow in 2-2). The MRI indicates stage IIB cervical cancer.
Figure 2.
Figure 2. Histological findings of surgical specimen of cervical tumor (H&E stain, original magnification × 40). Relatively large tumor cells invasively proliferate with organoid nesting pattern and central necrosis.
Figure 3.
Figure 3. Histological findings of surgical specimen of cervical tumor (H&E stain, original magnification × 200). Peripheral nuclear palisading and central necrosis are histologically observed.
Figure 4.
Figure 4. Histological findings of surgical specimen of cervical tumor ( H&E stain, original magnification × 400). Tumor cells exhibit abundant cytoplasm with vesicular nuclei. Mitotic activity of the tumor cell was high.
Figure 5.
Figure 5. Immunohistochemical findings of surgical specimen of cervical tumor (immunohistochemistry, original magnification × 100). Immunohistochemical staining of the tumor was strongly positive for synaptophysin (upper left), weakly positive for chromogranin-A (upper right) and partially positive for NCAM (bottom left). The Ki-67 index of the tumor cells was almost 100% (bottom right).