| Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc |
| Journal website http://www.jcgo.org |
Original Article
Volume 8, Number 3, September 2019, pages 77-80
Minimal Stimulation Using Letrozole in Poor Responders
Tables
| Variable | |
|---|---|
| AMH: anti-Mullerian hormone. | |
| Mean age (years) | 38.6 ± 3.5 |
| Mean AMH (ng/mL) | 0.4 ± 0.3 |
| Cycle | |
| First (n) | 14 |
| Second or more (n) | 29 |
| Number of oocytes received per patient | 2.5 ± 2.1 |
| Fertilization rate per patient (%) | 63.1 |
| Cleavage rate per patient (%) | 55.2 |
| Outcome of cycle, n (%) | |
| No oocytes obtained | 8 (18.6) |
| No embryos obtained | 4 (9.3) |
| No pregnancy | 22 (51.2) |
| Ectopic pregnancy | 1 (2.3) |
| Live birth | 8 (18.6) |
| Variable | Minimal stimulation protocol | Conventional IVF protocol | P value |
|---|---|---|---|
| *Statistically significant at P < 0.05. IVF: in vitro fertilization. | |||
| Number of oocytes received per patient | 2.1 ± 1.6 | 2.7 ± 1.6 | 0.17 |
| Fertilization rate per patient, % | 66.8 ± 33.8 | 47.9 ± 35.7 | 0.09 |
| Cleavage rate per patient, % | 61.3 ± 31.9 | 28.7 ± 29.4 | 0.002* |
| Outcome of cycle, n (%) | 0.13 | ||
| No oocytes obtained | 5 (20) | 4 (16) | |
| No embryos obtained | 2 (8) | 27 (28) | |
| No pregnancy | 14 (56) | 14 (56) | |
| Miscarriage/ectopic/abortion | 1 (4) | 0 | |
| Live birth | 3 (12) | 0 | |