Figure 1. Fetal heart rate (bpm) by estimated gestational age (weeks).
| Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc |
| Journal website http://www.jcgo.org |
Case Report
Volume 8, Number 3, September 2019, pages 91-96
Fetal Heart Rate as an Indirect Indicator of Treatment Response in Fetal Hyperthyroidism Secondary to Transplacental Passage of Maternal Thyrotropin Receptor Antibodies
Figure
Tables
| Date | EGA (weeks) | FHR (bpm) | Levothyroxine (µg PO qDay) | Methimazole (mg PO BID) | TSH (µIU/mL) | Free T4 (ng/mL) | Free T3 (pg/mL) | TRAb (U/L) | TSI index | Thyroid size (mm) | EFW (g) | EFW (percentile) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EGA: estimated gestational age; FHR: fetal heart rate; PO: per os; BID: twice daily; TSH: thyroid-stimulating hormone; TRAb: thyrotropin receptor antibody; TSI: thyroid-stimulating immunoglobulin; EFW: estimated fetal weight. | ||||||||||||
| 2014-12-11 | 15 + 3 | - | 100 | - | 46.7 | 1.4 | - | - | - | - | - | - |
| 2015-1-9 | 19 + 4 | 154 | 100 | - | 32.4 | - | - | - | - | - | - | - |
| 2015-2-2 | 23 | 180 | 175 | - | - | - | - | - | - | - | 518 | 25% |
| 2015-2-3 | 23 + 1 | 171 | 175 | - | - | - | - | - | - | 17 × 8 | - | - |
| 2015-2-5 | 23 + 3 | - | 175 | - | 12.6 | 1.17 | - | - | 447 | - | - | - |
| 2015-2-19 | 25 + 3 | 162 | 175 | - | 5.6 | 1.16 | - | - | 481 | 18 × 9 | - | - |
| 2015-3-2 | 27 | 176 | 175 | - | - | - | - | - | - | - | 911 | 15% |
| 2015-3-17 | 29 + 1 | 180 | 175 | 10 | 5.14 | 1.27 | - | - | - | 19 × 10 | - | - |
| 2015-3-20 | 29 + 4 | 192 | 175 | 10 | - | - | - | - | - | 23 × 13 | - | - |
| 2015-3-24 | 30 + 1 | 162 | 175 | 10 | - | - | - | - | - | 24 × 14 | - | - |
| 2015-3-27 | 30 + 4 | 157 | 200 | 10 | - | - | - | - | - | 21 × 13 | 1,422 | 13% |
| 2015-3-31 | 31 + 1 | 160 | 200 | 10 | - | - | - | - | - | 29 × 18 | - | - |
| 2015-4-3 | 31 + 4 | 157 | 200 | 5 | - | - | - | - | - | - | - | - |
| 2015-4-6 | 32 | 157 | 200 | 5 | - | - | - | - | - | - | - | - |
| 2017-4-7 | 32 + 1 | 153 | 200 | 5 | - | - | - | - | - | - | - | - |
| 2015-4-10 | 32 + 4 | 168 | 200 | 5 | 5.49 | 1.19 | 2.4 | 78.6 | - | - | 1,902 | 27% |
| 2015-4-14 | 33 + 1 | 167 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-4-21 | 34 + 1 | 160 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-4-24 | 34 + 4 | 159 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-4-28 | 35 + 1 | 161 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-5-1 | 35 + 4 | 153 | 200 | 10 | - | - | - | - | - | - | 2,297 | 12% |
| 2015-5-5 | 36 + 1 | 153 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-5-8 | 36 + 4 | 149 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-5-12 | 37 + 1 | 143 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-5-15 | 37 + 4 | 144 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-5-19 | 38 + 1 | 128 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-5-22 | 38 + 4 | 140 | 200 | 10 | - | - | - | - | - | - | 3,075 | 27% |
| 2015-5-26 | 39 + 1 | 141 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-5-29 | 39 + 4 | 143 | 200 | 10 | - | - | - | - | - | - | - | - |
| 2015-6-2 | 40 + 1 | 130 | 200 | 10 | 6.26 | 1.03 | 2 | - | - | - | 3,225 | - |
| Age | TSI index | TSH (µIU/mL) | Free T4 (ng/mL) |
|---|---|---|---|
| TSI: thyroid-stimulating immunoglobulin; TSH: thyroid-stimulating hormone. | |||
| Birth | 565 | < 0.03 | 7.05 |
| 1 Month | 149 | 0.1 | 0.69 |
| 2 Months | - | 0.85 | 0.86 |
| 3 Months | 58 | 1.07 | 1.04 |