Figure 1. Ovarian steroidogenesis, the role of 3β-HSD in the conversion of DHEA to androgens and estrogens in the adrenal glands and gonads. 3β-HSD: 3β-hydroxysteroid dehydrogenase; DHEA: dehydroepiandrosterone.
| Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc |
| Journal website https://www.jcgo.org |
Case Report
Volume 10, Number 2, June 2021, pages 51-54
Successful Management of Significant Maternal 3 Beta-Hydroxysteroid Dehydrogenase Deficiency
Figure
Table
| Time zero (normal values) | 1 h elapsed | |
|---|---|---|
| ACTH: adrenocorticotropic hormone; DHEA: dehydroepiandrosterone. | ||
| 17-hydroxyprogesterone | 392 mg/dL (10 - 120 mg/dL) | 271 mg/dL |
| Pregnenolone | 199 ng/dL | 497 ng/dL |
| 17-hydroxypregnenolone | 161 ng/dL (53 - 357 ng/dL) | 705 ng/dL |
| DHEA | 3.9 ng/mL (1.9 - 7.6 ng/mL) | 8.2 ng/mL |
| 11-deoxycortisol | 0.2 µg/dL (7 - 25 µg/dL) | 0.3 µg/dL |
| Cortisol | 16 µg/dL (7 - 25 µg/dL) | 27 µg/dL |
| Testosterone | 25 ng/dL (14 - 76 ng/dL) | 22 ng/dL |