J Clin Gynecol Obstet

Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc

Journal website https://www.jcgo.org

Case Report

Volume 10, Number 2, June 2021, pages 55-58

A Case of a Rare Malignant Mixed Ovarian Germ Cell Tumor Masquerading as an Ectopic Pregnancy

Figures

Figure 1. Laparoscopic view of the left ovarian mass presumed to be an ovarian ectopic.

Figure 2. Histopathological assessment identified a malignant mixed ovarian germ cell tumor. Yolk sac tumor (a) and choriocarcinoma (b) components by H&E staining are shown. Original magnifications are × 100. H&E: hematoxylin and eosin stain.

Table

**Table 1.** Comparison of Clinical Findings and Management of Malignant Ovarian Germ Cell Tumors Presenting as Apparent Ectopic Pregnancies
Reference	Histology	Symptoms	Investigations	Management
USS: ultrasound; β-hCG: beta-human chorionic gonadotrophin; TVS: transvaginal ultrasound; CT: computed tomography; AFP: alpha fetoprotein; TVUS: transvaginal ultrasound.
Kucera et al, 2017 [4]	Mixed germ cell tumor	Amenorrhoea	Left adnexal mass on USS, β-hCG: 2,121	Laparoscopy
Rozenholc et al, 2012 [3]	Mixed germ cell tumor	Amenorrhoea, right abdominal tenderness	Right adnexal mass on USS, β-hCG: 11,998	Laparoscopy
Ozkaya et al, 2005 [5]	Mixed germ cell tumor	Amenorrhoea, abdominal pain	Left adnexal mass on TVS and CT scan, raised AFP 2,172, β-hCG: 3,800	Exploratory laparotomy
Dawley et al, 2012 [6]	Mature teratoma	Amenorrhoea	No intrauterine pregnancy on TVS, β-hCG: 57,914	Laparoscopy
Balat et al, 2004 [7]	Ovarian choriocarcinoma	Irregular vaginal bleeding	Mass on TVS, β-hCG: 8.968	Exploratory laparotomy
Freij et al, 2011 [8]	Ovarian choriocarcinoma	Lower abdominal pain	Left ovarian mass on TVUS, β-hCG: 1,110.5	Laparoscopy
Horne et al, 2006 [9]	Ovarian choriocarcinoma	Lower abdominal pain, heavy vaginal bleeding	Right adnexal mass on TVUS, static β-hCG: 189	Methotrexate initially, laparoscopy when rising β-hCG