J Clin Gynecol Obstet

Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc

Journal website https://www.jcgo.org

Original Article

Volume 11, Number 3, September 2022, pages 69-74

Variation of the Cerebral Flow Dynamics in Mexican Pregnant Women During the Third Trimester

**Table 1.** General Characteristics
Variable	Mean ± SD
BMI: body mass index; SD: Standard deviations.
Weight (kg)	61.6 ± 5.80
Height (cm)	158.1 ± 5.9
BMI (kg/m²)	24.7 ± 2.2
Gestational age (weeks)	28.1 ± 11.2
< 32	22.1%
32 - 36	20.6%
> 37	57.4%
Maternal age (years)	21.8 ± 5.6
< 19	43.5%
20 - 29	44.9%
> 30	11.6%

Table 1. General Characteristics

Variable

Mean ± SD

BMI: body mass index; SD: Standard deviations.

Weight (kg)

61.6 ± 5.80

Height (cm)

158.1 ± 5.9

BMI (kg/m²)

24.7 ± 2.2

Gestational age (weeks)

28.1 ± 11.2

< 32

22.1%

32 - 36

20.6%

> 37

57.4%

Maternal age (years)

21.8 ± 5.6

< 19

43.5%

20 - 29

44.9%

> 30

11.6%

**Table 2.** Comparison of Hemodynamic and Doppler Values by Chronological Age
Characteristics	≤ 19 years	20 - 29 years	≥ 30 years	P value^a
^aANOVA test. *P < 0.05. MAP: mean arterial pressure; PSCV: peak systolic cerebral blood flow velocity; PDCV: peak diastolic cerebral blood flow velocity; MPCV: mean peak cerebral blood flow velocity; CPP: cerebral perfusion pressure; CRI: cerebral resistance index; BFI: brain flow index; ANOVA: analysis of variance.
Systemic blood pressure measurements
Systolic (mm Hg)	113.2 ± 9.9	114.2 ±12.0	115.6 ± 11.8	0.851
Diastolic (mm Hg)	69.7 ± 9.4	75.5 ± 8.1	75.0 ± 7.5	0.029*
MAP (mm Hg)	84.2 ± 8.6	88.2 ± 8.3	88.5 ± 7.4	0.144
Flow velocities
PSCV (cm/s)	55.4 ± 17.3	57.1 ± 20.6	55.0 ± 23.2	0.928
PDCV (cm/s)	21.8 ± 8.2	21.6 ± 8.9	22.2 ± 12.3	0.988
MPCV (cm/s)	32.3 ± 10.3	33.4 ± 12.7	32.6 ± 15.8	0.941
Cerebral perfusion measurements
CPP (mm Hg)	45.2 ± 11.1	36.3 ± 8.8	40.1 ± 12.1	0.005*
CRI	2.9 ± 1.0	2.9 ± 0.9	3.4 ± 1.7	0.481
BFI (cm/s)	17.8 ± 8.1	14.0 ± 6.6	15.1 ± 9.0	0.151

Table 2. Comparison of Hemodynamic and Doppler Values by Chronological Age

Characteristics

≤ 19 years

20 - 29 years

≥ 30 years

P value^a

^aANOVA test. *P < 0.05. MAP: mean arterial pressure; PSCV: peak systolic cerebral blood flow velocity; PDCV: peak diastolic cerebral blood flow velocity; MPCV: mean peak cerebral blood flow velocity; CPP: cerebral perfusion pressure; CRI: cerebral resistance index; BFI: brain flow index; ANOVA: analysis of variance.

Systemic blood pressure measurements

Systolic (mm Hg)

113.2 ± 9.9

114.2 ±12.0

115.6 ± 11.8

0.851

Diastolic (mm Hg)

69.7 ± 9.4

75.5 ± 8.1

75.0 ± 7.5

0.029*

MAP (mm Hg)

84.2 ± 8.6

88.2 ± 8.3

88.5 ± 7.4

0.144

Flow velocities

PSCV (cm/s)

55.4 ± 17.3

57.1 ± 20.6

55.0 ± 23.2

0.928

PDCV (cm/s)

21.8 ± 8.2

21.6 ± 8.9

22.2 ± 12.3

0.988

MPCV (cm/s)

32.3 ± 10.3

33.4 ± 12.7

32.6 ± 15.8

0.941

Cerebral perfusion measurements

CPP (mm Hg)

45.2 ± 11.1

36.3 ± 8.8

40.1 ± 12.1

0.005*

CRI

2.9 ± 1.0

2.9 ± 0.9

3.4 ± 1.7

0.481

BFI (cm/s)

17.8 ± 8.1

14.0 ± 6.6

15.1 ± 9.0

0.151

**Table 3.** Comparison of Doppler Figures by Gestational Age
Parameters	≤ 32 weeks (n = 14)	32 - 36 weeks (n = 15)	≥ 37 weeks (n = 39)	P value^a
^aANOVA. **P < 0.05. MAP: mean arterial pressure; PSCV: peak systolic cerebral blood flow velocity; PDCV: peak diastolic cerebral blood flow velocity; MPCV: mean peak cerebral blood flow velocity; CPP: cerebral perfusion pressure; CRI: cerebral resistance; BFI: brain flow index; ANOVA: analysis of variance.
Systemic blood pressure measurements
Systolic (mm Hg)	113.2 ± 9.9	114.2 ± 12.0	115.6 ± 11.8	0.689
Diastolic (mm Hg)	71.3 ± 8.3	71.8 ± 6.7	73.7 ± 9.9	0.618
MAP (mm Hg)	85.3 ± 7.4	85.3 ± 7.3	86.4 ± 8.5	0.684
Comparison of Doppler
CPP (mm Hg)	41.0 ± 8.1	42.8 ± 12.8	40.1 ± 11.3	0.719
CRI	3.1 ± 0.8	2.3 ± 0.9	3.4 ± 1.7	0.028**
BFI (cm/s)	17.8 ± 8.1	14.0 ± 6.6	15.1 ± 9.0	0.007^a
Flow velocities
PSCV (cm/s)	52.4 ± 16.2	74.2 ± 25.8	51.5 ± 13.6	< 0.000**
PDCV (cm/s)	19.4 ± 6.4	29.5 ± 11.8	20.2 ± 6.9	0.001**
MPCV (cm/s)	29.5 ± 8.7	43.6 ± 16.2	30.6 ± 8.8	0.001**

Table 3. Comparison of Doppler Figures by Gestational Age

Parameters

≤ 32 weeks (n = 14)

32 - 36 weeks (n = 15)

≥ 37 weeks (n = 39)

P value^a

^aANOVA. **P < 0.05. MAP: mean arterial pressure; PSCV: peak systolic cerebral blood flow velocity; PDCV: peak diastolic cerebral blood flow velocity; MPCV: mean peak cerebral blood flow velocity; CPP: cerebral perfusion pressure; CRI: cerebral resistance; BFI: brain flow index; ANOVA: analysis of variance.

Systemic blood pressure measurements

Systolic (mm Hg)

113.2 ± 9.9

114.2 ± 12.0

115.6 ± 11.8

0.689

Diastolic (mm Hg)

71.3 ± 8.3

71.8 ± 6.7

73.7 ± 9.9

0.618

MAP (mm Hg)

85.3 ± 7.4

85.3 ± 7.3

86.4 ± 8.5

0.684

Comparison of Doppler

CPP (mm Hg)

41.0 ± 8.1

42.8 ± 12.8

40.1 ± 11.3

0.719

CRI

3.1 ± 0.8

2.3 ± 0.9

3.4 ± 1.7

0.028**

BFI (cm/s)

17.8 ± 8.1

14.0 ± 6.6

15.1 ± 9.0

0.007^a

Flow velocities

PSCV (cm/s)

52.4 ± 16.2

74.2 ± 25.8

51.5 ± 13.6

< 0.000**

PDCV (cm/s)

19.4 ± 6.4

29.5 ± 11.8

20.2 ± 6.9

0.001**

MPCV (cm/s)

29.5 ± 8.7

43.6 ± 16.2

30.6 ± 8.8

0.001**