Evaluation of the Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Patients With Ectopic Pregnancies

Servet Gencdal, Huseyin Aydogmus, Nihan Kiziltug Gencdal, Emre Destegul, Emre Ekmekci


Background: The aim of this study was to evaluate hematologic parameters in ectopic pregnancy.

Methods: This retrospective study was conducted at Izmir Katip Celebi University Ataturk Education and Research Hospital between January 2016 and June 2017. The medical records of 97 patients hospitalised for ectopic pregnancy (EP) were summarised. The control group consisted of 112 women at 6 - 8 weeks, healthy, intrauterine gestations as confirmed by ultrasound (positive fetal heart rates). Hematologic parameters including white blood cells, hemoglobin and platelet counts, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and mean platelet volume (MPV) were compared.

Results: In total, 209 patients were included in the study: 112 with healthy pregnancies and 97 with EPs. There was no statistically significant difference between the groups regarding mean age, gravidity, parity, number of abortions, body mass index, history for previous cesarean deliveries, and previous EPs. The MPV level was lower in the EP group than in the control group. In addition, the mean NLR was higher in the EP group than in the controls.

Conclusions: Considering the sensitivity and specificity, overall, the NLR and MPV has moderate diagnostic potential in patients with ectopic pregnancies.

J Clin Gynecol Obstet. 2019;8(3):81-84
doi: https://doi.org/10.14740/jcgo559



Ectopic pregnancy; Neutrophil-lymphocyte ratio; Platelet-lymphocyte ratio

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