Transient Osteoporosis of the Knees, Ankles and Feet: Atypical Case in a Twin Pregnancy

Tatiana Elizabeth Carranco-Medina, Ismael Calero-Paniagua, Cristina Hidalgo-Calleja, Maria Dolores Sanchez-Gonzalez, Carlos Alberto Montilla-Morales, Alba Quesada-Moreno, Ricardo Usategui-Martin, Laura Perez-Garrido, Susana Gomez-Castro, Olga Martinez-Gonzalez, Javier Del Pino-Montes


Transient osteoporosis (TO) is a rare entity with unknown origin which is, in most cases, self-limiting. The most common location is the hip, which can sometimes be bilateral, followed by the knee, ankle and foot. The multifocal, bilateral and simultaneous location of knees, ankles and feet during pregnancy is extremely rare. We present the case of a woman, 25 weeks pregnant with twins, who was admitted as an emergency with pain and functional disability of her lower limbs. She required hospitalization and was diagnosed with transient osteoporosis of pregnancy (TOP), with clinical and radiological resolution after 12 months and treatment with intravenous bisphosphonate.

J Clin Gynecol Obstet. 2016;5(1):37-40


Transient osteoporosis; Transient bone marrow edema syndrome; Pregnancy; Twins

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