Comparison of Dinoprostone Vaginal Tablet and Vaginal Insert in Primigravid Women for Induction of Labor

Abstract

Background: Labor of induction by use of different drugs is generally preferred for avoiding complications with prolonged pregnancy. Dinoprostone vaginal gel or insert tablets are commonly used for inducing contractions similar to normal delivery contractions. The current study compares the effectiveness of dinoprostone vaginal tablet and dinoprostone vaginal insert in induction of labor for primigravid women.

Methods: The participants of the prospective cohort observational study were primigravid women. BISHOP score was used as a tool for predicting patient who required labor induction. All the participants with BISHOP score less than 6 were given either dinoprostone vaginal tablet or dinoprostone vaginal insert for induction of labor. Chi-square statistical analysis was performed using SPSS, version 17.0.

Results: A total of 135 patients were studied. Post-term pregnancy was found to be most common indication among studied patients. Labor induction was executed by using dinoprostone vaginal tablet and insert in 61% and 31% patients, respectively. Statistically, no significant differences were found in the rate of cesarean section among two treatment regimens on applying Chi-square analysis. On average, two dinoprostone tablets per patient as compared to one vaginal insert were used for labor induction.

Conclusion: Dinoprostone vaginal tablet and vaginal insert both have similar efficacy in induction of labor to be used in primigravid women.




J Clin Gynecol Obstet. 2018;7(2):52-56
doi: https://doi.org/10.14740/jcgo471w