A Rare Case of Transformation of Endometrial Carcinoma Into Uterine Carcinosarcoma

Abstract

Uterine carcinosarcoma (previously called malignant mixed Mullerian tumor) is a rare and aggressive cancer that is considered a high-risk variant of endometrial adenocarcinoma because of the resemblance in risk factors and clinical presentation with endometrial carcinoma. In the United States, the incidence of carcinosarcoma is approximately 1 to 4 per 100,000 women. The clinical features, diagnosis, staging, and treatment of uterine carcinosarcoma will be discussed in this topic review. To our knowledge, this is one of the few reported cases of endometrial carcinoma that has transformed into uterine carcinosarcoma.

J Clin Gynecol Obstet. 2021;10(3):81-85
doi: https://doi.org/10.14740/jcgo677