Resistant Ovary Syndrome Masquerading as Premature Ovarian Insufficiency
Irene Woo, Yulan Zhang, Hongxia Hui, Eliran Mor
Abstract
Premature ovarian insufficiency (POI) is typically the end result of premature depletion of primordial follicles. However gonadotropin-resistant ovary syndrome could result in a similar clinical and laboratory picture with a more favorable outcome. A 29-year-old G0 woman with POI referred to our infertility clinic for egg donation. On ultrasound, her ovaries contained multiple resting antral follicles (AFs). Patient underwent transvaginal ultrasound-guided follicle aspiration of all visible small antral follicles. Eggs were
in vitro matured and resulting embryos cryopreserved. Patient achieved a successful live birth with her own eggs. Gonadotropin-resistant ovary syndrome must be considered in all women diagnosed with hypergonadotropic hypogonadal POI and normal antral follicle count (AFC) and anti-Mullerian hormone (AMH). In these patients, pregnancy can be achieved with their own eggs.
J Clin Gynecol Obstet. 2019;8(4):111-113
doi: https://doi.org/10.14740/jcgo575
Keywords
Resistant ovary syndrome; Premature ovarian insufficiency; IVF
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