Endometrial Stromal Sarcoma in the Young

Abstract

Endometrial stromal sarcoma (ESS) represents a very rare group of malignant tumors comprising less than 10% of all uterine sarcomas but only around 0.2% of all uterine cancer. In developing countries, the prevalence of ESS is approximately two in a million perimenopausal women between ages of 45 and 50 years. The occurrence in younger women is rare and the diagnosis frequently delayed due to low index of suspicion. Two cases of ESS diagnosed in women in the 20s age group were documented in a tertiary hospital. Both patients presented with abnormal vaginal bleeding associated with hypogastric pain and rapid abdominal enlargement. Surgery was the primary treatment modality and histopathologic examination confirmed the diagnosis. Adjuvant therapy remains controversial. ESS is a rare pathological entity, more so in the young. However, the diagnosis of a malignancy should not be missed despite rarity of occurrence in this age group.

J Clin Gynecol Obstet. 2020;9(3):73-77
doi: https://doi.org/10.14740/jcgo647